Left atrial appendage closure in patients with atrial fibrillation in whom warfarin is contra-indicated: initial South African experience
نویسنده
چکیده
Atrial fibrillation is a common cause of cardiac embolic events, especially stroke. Oral anticoagulation therapy is used to reduce these events. Many patients however are unable to take such therapy. Percutaneous occlusion of the left atrial appendage (the source of 90% of these emboli) is an option in these patients. Presented here are the first 12 patients to have this procedure done in South Africa.
منابع مشابه
Percutaneous closure of the left atrial appendage for prevention of thromboembolism in atrial fibrillation for patients with contraindication to or failure of oral anticoagulation: a single-center experience.
INTRODUCTION In non-valvular atrial fibrillation 90% of thrombi originate in the left atrial appendage (LAA). Percutaneous LAA closure has been shown to be non-inferior to warfarin for prevention of thromboembolism. OBJECTIVE To evaluate the initial experience of a single center in percutaneous LAA closure in patients with high thromboembolic risk and in whom oral anticoagulation was impracti...
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Background: Mechanical occlusion of the Left atrial appendage (LAA) using a purpose-built device has emerged as an effective prophylactic treatment in patients with atrial fibrillation at risk of stroke and a contraindication for anticoagulation. A crucial step in procedural planning is the choice of the device size. This is currently based on the manual analysis of the “Device Landing Zone” fr...
متن کاملCardioembolic Stroke in Atrial Fibrillation-Rationale for Preventive Closure of the Left Atrial Appendage
Atrial fibrillation is the most common cardiac arrhythmias, and a major cause of morbidity and mortality due to cardioembolic stroke. The left atrial appendage is the major site of thrombus formation in non-valvular atrial fibrillation. Loss of atrial systole in atrial fibrillation and increased relative risk of associated stroke point strongly toward a role for stasis of blood in left atrial t...
متن کاملThe Evolving Landscape of Thromboembolic Disease: Diagnostic and Management Strategies.
This issue of the Rhode Island Medical Journal focuses on the broad topic of thromboembolic disease, its many and varied clinical presentations, their incidence, symptoms, diagnostic evaluation and, most importantly, their unique management and treatment strategies. DRS. P. RILEY, A. MAAN and K.S. KORR open with an update on the current status of the Direct-Acting Oral Anticoagulants (DOACs), f...
متن کاملPercutaneous left atrial appendage closure for stroke prophylaxis in patients with atrial fibrillation: 2.3-Year Follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients with Atrial Fibrillation) Trial.
BACKGROUND The multicenter PROTECT AF study (Watchman Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation) was conducted to determine whether percutaneous left atrial appendage closure with a filter device (Watchman) was noninferior to warfarin for stroke prevention in atrial fibrillation. METHODS AND RESULTS Patients (n=707) with nonvalvular atrial fibril...
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عنوان ژورنال:
دوره 24 شماره
صفحات -
تاریخ انتشار 2013